BSI PD ISO/TS 5387:2023
$167.15
Nanotechnologies. Lung burden mass measurement of nanomaterials for inhalation toxicity tests
| Published By | Publication Date | Number of Pages |
| BSI | 2023 | 34 |
PDF Catalog
| PDF Pages | PDF Title |
|---|---|
| 2 | undefined |
| 6 | Foreword |
| 7 | Introduction |
| 9 | 1 Scope 2 Normative references 3 Terms and definitions |
| 12 | 4 Abbreviated terms 5 Use of lung burden measurements for risk assessment of nanomaterials |
| 13 | 6 Inhalation exposure and tissue sampling to determine lung burden 6.1 Inhalation exposure 6.2 Lung burden evaluation in single or multiple lobes |
| 14 | 6.3 Post-exposure observation points |
| 15 | 7 Available methods for lung burden measurements 7.1 General |
| 16 | 7.2 Carbon nanomaterials 7.3 Metal-based nanomaterials |
| 17 | 7.4 Polymeric nanomaterials and others 8 Application of lung burden data to toxicokinetics of nanomaterials 8.1 General 8.2 Sampling points |
| 18 | 8.3 Particle lung clearance and retention kinetics 8.3.1 General 8.3.2 One-compartment first-order clearance model |
| 19 | 8.3.3 Two-compartment first-order model |
| 23 | Annex A (informative) Option A for test scheme for 28-d and 90-d studies — Gases, vapours, liquid aerosols, and fast dissolution solid aerosols |
| 24 | Annex B (informative) Option B for test schemes for 28-d and 90-d studies — Poorly soluble aerosols |
| 25 | Annex C (informative) Lung burden measurement methods |
| 29 | Bibliography |
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