{"id":453550,"date":"2024-10-20T09:30:53","date_gmt":"2024-10-20T09:30:53","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-iso-20688-22024\/"},"modified":"2024-10-26T17:38:52","modified_gmt":"2024-10-26T17:38:52","slug":"bs-iso-20688-22024","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-iso-20688-22024\/","title":{"rendered":"BS ISO 20688-2:2024"},"content":{"rendered":"
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
---|---|---|---|---|---|---|---|
2<\/td>\n | undefined <\/td>\n<\/tr>\n | ||||||
7<\/td>\n | Foreword <\/td>\n<\/tr>\n | ||||||
8<\/td>\n | Introduction <\/td>\n<\/tr>\n | ||||||
9<\/td>\n | 1 Scope 2 Normative references 3 Terms and definitions <\/td>\n<\/tr>\n | ||||||
11<\/td>\n | 4 Requirements for quality management 4.1 General requirements <\/td>\n<\/tr>\n | ||||||
12<\/td>\n | 4.2 Control of documents <\/td>\n<\/tr>\n | ||||||
13<\/td>\n | 4.3 Quality management system 4.4 Biorisk management and safety control 5 Requirements for resource management 5.1 Facilities and environmental condition 5.2 Equipment and instruments <\/td>\n<\/tr>\n | ||||||
14<\/td>\n | 5.3 Raw materials 5.4 Personnel 6 Biosafety and biosecurity requirements 6.1 General 6.2 DNA sequence screening mechanism <\/td>\n<\/tr>\n | ||||||
15<\/td>\n | 7 Requirements for quality control in production 7.1 General 7.2 Quality control in synthetic gene fragments production 7.2.1 General 7.2.2 Sequence design <\/td>\n<\/tr>\n | ||||||
16<\/td>\n | 7.2.3 Assembly 7.2.4 Purification 7.2.5 Product preservation 7.3 Quality control in synthetic gene production 7.3.1 General 7.3.2 Colony screening 7.3.3 DNA preparation from the host cell <\/td>\n<\/tr>\n | ||||||
17<\/td>\n | 7.3.4 Sequence verification 7.3.5 Product preservation 7.4 Quality control in synthetic genome production 7.4.1 General 7.4.2 Assembly 7.4.3 Sequence verification <\/td>\n<\/tr>\n | ||||||
18<\/td>\n | 8 Requirements for product quality 8.1 Synthetic gene fragments 8.1.1 General 8.1.2 Yield 8.1.3 Purity 8.1.4 Size 8.1.5 Gene cloning accuracy 8.2 Synthetic genes 8.2.1 General 8.2.2 Yield <\/td>\n<\/tr>\n | ||||||
19<\/td>\n | 8.2.3 Purity 8.2.4 Sequence 8.2.5 Integrity 8.2.6 Residual impurities analysis <\/td>\n<\/tr>\n | ||||||
20<\/td>\n | 8.2.7 Supercoiled plasmid 8.2.8 Bioburden 8.2.9 Specific quality indicators for synthetic DNA libraries 8.3 Synthetic genome 8.3.1 General 8.3.2 Sequence <\/td>\n<\/tr>\n | ||||||
21<\/td>\n | 9 Delivered\/synthesized material specifications 9.1 Main information 9.2 Other information <\/td>\n<\/tr>\n | ||||||
22<\/td>\n | Annex A (informative) Example equipment and device list and their control requirements <\/td>\n<\/tr>\n | ||||||
24<\/td>\n | Annex B (informative) Exemplary quality measurement methods <\/td>\n<\/tr>\n | ||||||
26<\/td>\n | Annex C (informative) Electrophoretogram <\/td>\n<\/tr>\n | ||||||
30<\/td>\n | Annex D (informative) Sanger sequencing <\/td>\n<\/tr>\n | ||||||
31<\/td>\n | Annex E (informative) Massively parallel sequencing <\/td>\n<\/tr>\n | ||||||
34<\/td>\n | Annex F (informative) Additional quality control options for synthetic gene fragments <\/td>\n<\/tr>\n | ||||||
36<\/td>\n | Annex G (informative) Example ranking of the risk posed by DNA products <\/td>\n<\/tr>\n | ||||||
37<\/td>\n | Bibliography <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" Biotechnology. Nucleic acid synthesis – Requirements for the production and quality control of synthesized gene fragments, genes, and genomes<\/b><\/p>\n |